18,19-Dehydrobuprenorphine

CAS: 155203-05-7

Ref. TR-D229310

Informação sobre produto

• Nome: 18,19-Dehydrobuprenorphine
• Sinónimos: (aS,5a,7a)-17-(Cyclopropylmethyl)-a-(1,1-dimethylethyl)-4,5-epoxy-3-hydroxy-6-methoxy-a-methyl-6,14-ethenomorphinan-7-methanol, 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-a-(1,1-dimethylethyl)-4,5-epoxy-3-hydroxy-6-methoxy-a-methyl-, [5a,7a(S)]-, HS 599, (2S)-2-[17-(cyclopropylmethyl)-4,5a-epoxy-3-hydroxy-6-methoxy-6a,14-etheno-14a-morphinan-7a-yl]-3,3-dimethylbutan-2-ol, Buprenorphine Imp. J (EP)
• CAS: 155203-05-7

Descrição

Applications An analogue of Buprenorphine (B689570) which displays high affinity and selectivity for μ-opioid receptors. It acts as an antinociceptive agent and potent analgesic.
References Lattanzi, R. et al.: Life. Sci., 70, 2177 (2002); Lattanzi, R. et al.: Brit. J. Pharmacol., 134, 441 (2001);

• Marca: TRC

Propriedades químicas

• Peso molecular: 465.62
• Fórmula: C₂₉H₃₉NO₄
• Cor/forma: Neat
• InChI: InChI=1S/C29H39NO4/c1-25(2,3)26(4,32)20-15-27-10-11-29(20,33-5)24-28(27)12-13-30(16-17-6-7-17)21(27)14-18-8-9-19(31)23(34-24)22(18)28/h8-11,17,20-21,24,31-32H,6-7,12-16H2,1-5H3/t20-,21-,24-,26+,27-,28+,29-/m1/s1
• Chave InChI: InChIKey=XXEUUFWMPBSHCE-DHCTZRPISA-N
• SMILES: CO[C@]12C=C[C@@]3(C[C@@H]1C(C)(O)C(C)(C)C)[C@H]1Cc4ccc(O)c5c4[C@@]3(CCN1CC1CC1)[C@H]2O5