N-Demethyl Rifampicin

CAS: 13292-45-0

Ref. TR-D231250

Informação sobre produto

• Nome: N-Demethyl Rifampicin
• Sinónimos: 3-[(1-Piperazinylimino)methyl]-rifamycin, 3-Piperazinoiminomethyl Rifamycin SV, 4-N-Demethylrifampicin, AF/AP, Demethylrifampicin, N-Demethylrifampicin, N-Demethylrifampin, NSC 143416, Rifampicin AF/AP, Rifampin, (2S,8E,16S,17S,18R,19R,20R,22R,23S,24E)-5,6,17,19-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,9,11-trioxo-8-[(piperazin-1-ylamino)methylidene]-1,2,8,9-tetrahydro-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-21-yl acetate, 2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan, rifamycin deriv., 2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-(N-1-piperazinylformimidoyl)-, 21-acetate, Af/Ap, Rifamycin, 3-[(1-piperazinylimino)methyl]-

Descrição

Applications N-Demethyl Rifampicin is a metabolite of Rifampicin (R508000).
References Marsili, L., et al.: J. Antibiot., 37, 1209 (1984), Nikaido, H., et al.: Antimicrob. Ag. Chemother., 37, 1393 (1993), Piddock, L., et al.: J. Antimicrob. Chemother., 45, 159 (2000),

• Marca: TRC

Propriedades químicas

• Peso molecular: 808.91
• Fórmula: C₄₂H₅₆N₄O₁₂
• Cor/forma: Red Crystalline Powder
• InChI: InChI=1S/C42H56N4O12/c1-20-11-10-12-21(2)41(54)45-32-27(19-44-46-16-14-43-15-17-46)36(51)29-30(37(32)52)35(50)25(6)39-31(29)40(53)42(8,58-39)56-18-13-28(55-9)22(3)38(57-26(7)47)24(5)34(49)23(4)33(20)48/h10-13,18-20,22-24,28,33-34,38,43,48-52H,14-17H2,1-9H3,(H,45,54)/b11-10+,18-13+,21-12-,44-19+/t20-,22+,23+,24+,28-,33-,34+,38+,42-/m0/s1
• Chave InChI: InChIKey=FKKVFHDDYXJFFL-VIVOQTQZSA-N
• SMILES: CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(c(/C=N/N5CCNCC5)c(O)c4c3C2=O)NC(=O)/C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C