(R)-N-Desacryloyl N-3-Chloropropionyl Ibrutinib

CAS: 1288338-96-4

Ref. TR-D288110

Informação sobre produto

• Nome: (R)-N-Desacryloyl N-3-Chloropropionyl Ibrutinib
• Sinónimos: (R)-N-Desacryloyl N-3-Propionyl Ibrutinib, 1-Propanone, 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-3-chloro- (ACI), 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-3-chloro-1-propanone (ACI), (R)-1-[3-[4-Amino-3-(
• Marca: TRC
• Descrição: Applications (R)-N-Desacryloyl N-3-Propionyl Ibrutinib is an impurity of Ibrutinib (I124970), which is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.References MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)

Propriedades químicas

• Peso molecular: 476.958
• Fórmula: C₂₅H₂₅ClN₆O₂
• Cor/forma: Neat
• InChI: InChI=1S/C25H25ClN6O2/c26-13-12-21(33)31-14-4-5-18(15-31)32-25-22(24(27)28-16-29-25)23(30-32)17-8-10-20(11-9-17)34-19-6-2-1-3-7-19/h1-3,6-11,16,18H,4-5,12-15H2,(H2,27,28,29)/t18-/m1/s1
• Chave InChI: InChIKey=VJQOEGZWPHTCTQ-GOSISDBHSA-N
• SMILES: Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2[C@@H]1CCCN(C(=O)CCCl)C1