N2-Des(L-valinyl) Lopinavir N2,O5-Oxazine

Ref. TR-D288220

Informação sobre produto

• Nome: N2-Des(L-valinyl) Lopinavir N2,O5-Oxazine
• Sinónimos: N-((S)-1-((4S,6S)-4-Benzyl-2-oxo-1,3-oxazinan-6-yl)-2-phenylethyl)-2-(2,6-dimethylphenoxy)acetamide

Descrição

Applications N2-Des(L-valinyl) Lopinavir N2,O5-oxazine is a metabolite of Lopinavir (L469480); a selective HIV protease inhibitor and antiviral. It is a COVID19-related research product.
References Sham, H.L., et al.: Antimicrob. Ag. Chemother., 42, 3218 (1998); Kumar, G.N., et al.: Drug Metab. Dispos., 27, 86 (1999); Murphy, R.L., et al.: Antiviral Ther., 4, Suppl. 3, 85 (1999)

• Marca: TRC

Propriedades químicas

• Peso molecular: 472.58
• Fórmula: C₂₉H₃₂N₂O₄
• Cor/forma: Off-white solid
• InChI: InChI=1S/C29H32N2O4/c1-20-10-9-11-21(2)28(20)34-19-27(32)31-25(17-23-14-7-4-8-15-23)26-18-24(30-29(33)35-26)16-22-12-5-3-6-13-22/h3-15,24-26H,16-19H2,1-2H3,(H,30,33)(H,31,32)/t24-,25-,26-/m0/s1
• Chave InChI: InChIKey=XAMVJQYRFDXGPR-GSDHBNRESA-N
• SMILES: Cc1cccc(C)c1OCC(=O)N[C@@H](Cc1ccccc1)[C@@H]1C[C@H](Cc2ccccc2)NC(=O)O1