2-Deschlorothien-3-yl Tioconazole Hydrochloride

CAS: 61709-33-9

Ref. TR-D289560

Informação sobre produto

• Nome: 2-Deschlorothien-3-yl Tioconazole Hydrochloride
• Sinónimos: Tioconazole USP Related Compound A, Tioconazole USP RC A,1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-(3-thienylmethoxy)ethyl]-, hydrochloride (1:1), 1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-(3-thienylmethoxy)ethyl]-, monohydrochloride (9CI), Tioconazole Imp. A (EP), Tioconazole Related Compound A as Hydrochloride, Tioconazole Impurity A as Hydrochloride
• CAS: 61709-33-9

Descrição

Applications 2-Deschloro Tioconazole Hydrochloride is an analog of Tioconazole (T444680), an antifungal that is more active than Fluconazole (F421000) or Voriconazole (V760000) against Candida glabrata mutant strains. Antifungal (topical).
References Jevons, S., et al.: Antimicrob. Agents Chemother., 15, 597 (1979), Clayton, Y.M., et al.: Clin. Exp. Dermatol., 7, 543 (1982), Marriott, M.S., et al.: Dermatologica, 166, 1 (1983),

• Marca: TRC

Propriedades químicas

• Peso molecular: 389.73
• Fórmula: C₁₆H₁₅Cl₃N₂OS
• Cor/forma: Neat
• InChI: /h1-7,10-11,16H,8-9H2, InChI=1S/C16H14Cl2N2OS.ClH/c17-13-1-2-14(15(18)7-13)16(8-20-5-4-19-11-20)21-9-12-3-6-22-10-12, 1H
• Chave InChI: InChIKey=VWTMBCHKRFCFFM-CCZBSFLLSA-N
• SMILES: OC[C@H]1C(O)C(O)[C@@H](CO)N1C(c1ccccc1)c1ccccc1