Desisobutyryl Ciclesonide-d11 (Mixture of Diastereomers)

CAS: 204444-44-0

Ref. TR-D290102

Informação sobre produto

• Nome: Desisobutyryl Ciclesonide-d11 (Mixture of Diastereomers)
• Sinónimos: (11β,16α)-16,17-[[(R/S)-Cyclohexyl-d11-methylene]bis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione, CIC-AP-d11, Ciclesonide active principle-d11
• Marca: TRC

Descrição

Applications Preclinical profile of Ciclesonide, a novel corticosteroid for the treatment of asthma. This compound is a mixture of diastereomers at the cyclohexyl acetal.
References Austin, R., et al.: Eur. Respir. J., 20, 1386 (2002), Belvisi, M.G., et al.: J. Pharmacol. Exp. Ther., 314, 568 (2005), Richter, K., et al.: J. Clin. Pharmacol., 45, 146 ( 2005).

Propriedades químicas

• Peso molecular: 481.67
• Fórmula: C₂₈₂H₁₁H₂₇O₆
• Cor/forma: Neat
• InChI: InChI=1S/C28H38O6/c1-26-11-10-18(30)12-17(26)8-9-19-20-13-23-28(22(32)15-29,27(20,2)14-21(31)24(19)26)34-25(33-23)16-6-4-3-5-7-16/h10-12,16,19-21,23-25,29,31H,3-9,13-15H2,1-2H3/t19-,20-,21-,23+,24+,25?,26-,27-,28+/m0/s1/i3D2,4D2,5D2,6D2,7D2,16D
• Chave InChI: InChIKey=OXPLANUPKBHPMS-VFCFKYEJSA-N
• SMILES: [2H]C1([2H])C([2H])([2H])C([2H])([2H])C([2H])(C2O[C@@H]3C[C@H]4[C@@H]5CCC6=CC(=O)C=C[C@]6(C)[C@H]5[C@@H](O)C[C@]4(C)[C@]3(C(=O)CO)O2)C([2H])([2H])C1([2H])[2H]