6-O-Desmethoxyethyl-6-O-chloroethyl Erlotinib Hydrochloride

CAS: 183320-04-9

Ref. TR-D290370

Informação sobre produto

• Nome: 6-O-Desmethoxyethyl-6-O-chloroethyl Erlotinib Hydrochloride
• Sinónimos: 6-(2-Chloroethoxy)-N-(3-ethynylphenyl)-7-(2-methoxyethoxy)-4-quinazolinamine Hydrochloride (1:1), 6-(2-Chloroethoxy)-N-(3-ethynylphenyl)-7-(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride, 4-Quinazolinamine, 6-(2-chloroethoxy)-N-(3-ethynylphenyl)-7-(2-methoxyethoxy)-, hydrochloride (1:1), 4-Quinazolinamine, 6-(2-chloroethoxy)-N-(3-ethynylphenyl)-7-(2-methoxyethoxy)-, monohydrochloride

Descrição

Applications 6-O-Desmethoxyethyl-6-O-chloroethyl Erlotinib hydrochloride is a derivative of Erlotinib (E625000), an epidermal growth factor receptor inhibitor and tyrosine kinase inhibitor that is used to treat patients with lung cancer.
References Herbst, R., et al.: J. Clin. Oncol., 23, 5892 (2005); Pérez-Soler, R., et al.: J. Clin. Oncol., 22, 3238 (2004); Shepherd, F., et al.: New Engl. J. Med., 353, 123 (2005)

• Marca: TRC

Propriedades químicas

• Peso molecular: 434.32
• Fórmula: C₂₁H₂₁Cl₂N₃O₃
• Cor/forma: White to Off-White Solid
• InChI: InChI=1S/CH4/h1H4
• Chave InChI: InChIKey=VNWKTOKETHGBQD-UHFFFAOYSA-N
• SMILES: C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCCl)cc23)c1.Cl