4-Des((3-methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl)-4-hydroxy-N-(tert-butyl formate) Teneligliptin

CAS: 401564-34-9

Ref. TR-D293875

Informação sobre produto

• Nome: 4-Des((3-methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl)-4-hydroxy-N-(tert-butyl formate) Teneligliptin
• Sinónimos: (2S,4S)-Tert-Butyl 4-Hydroxy-2-(Thiazolidine-3-Carbonyl)Pyrrolidine-1-Carboxylate
• Marca: TRC
• Descrição: Applications 4-Des((3-methyl-1-phenyl-1H-pyrazol-5-yl)-1-piperazinyl)-4-hydroxy-N-(tert-butyl formate) Teneligliptin is a possible impurity of Teneligliptin (T018295), a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used to treat type 2 diabetes. It is eliminated via excretion, and has a half-life of 24.2 hours in the human body.References Goda, M. & Kadowaki, T.: Drugs Today, 49, 615 (2013); Kishimoto, M.: Diabetes Metab. Syndr. Obes., 6, 187 (2012)

Propriedades químicas

• Peso molecular: 302.39
• Fórmula: C₁₃H₂₂N₂O₄S
• Cor/forma: Neat
• InChI: InChI=1S/C13H22N2O4S/c1-13(2,3)19-12(18)15-7-9(16)6-10(15)11(17)14-4-5-20-8-14/h9-10,16H,4-8H2,1-3H3/t9-,10-/m0/s1
• Chave InChI: InChIKey=CABJFRFFUZMDSS-UWVGGRQHSA-N
• SMILES: CC(C)(C)OC(=O)N1C[C@@H](O)C[C@H]1C(=O)N1CCSC1