4-((2,4-Dichloro-5-methoxyphenyl)amino)-7-(3-(dimethylamino)propoxy)-6-methoxyquinoline-3-carbonitrile Dimer

CAS: 2095306-26-4

Ref. TR-D424570

Informação sobre produto

• Nome: 4-((2,4-Dichloro-5-methoxyphenyl)amino)-7-(3-(dimethylamino)propoxy)-6-methoxyquinoline-3-carbonitrile Dimer
• Sinónimos: 4-((2,4-Dichloro-5-methoxyphenyl)amino)-7-(3-(4-(3-((4-((2,4-dichloro-5-methoxyphenyl)amino)-3-isocyano-6-methoxyquinolin-7-yl)oxy)propyl)piperazin-1-yl)propoxy)-6-methoxyquinoline-3-carbonitrile, Bosutinib dimer
• Marca: TRC
• Descrição: Applications 4-((2,4-Dichloro-5-methoxyphenyl)amino)-7-(3-(4-(3-((4-((2,4-dichloro-5-methoxyphenyl)amino)-3-isocyano-6-methoxyquinolin-7-yl)oxy)propyl)piperazin-1-yl)propoxy)-6-methoxyquinoline-3-carbonitrile is a reactant used in the preparation of Bosutinib (B676095).References Soni, J., et al.: Indian Pat. Appl. (2016), IN 2014MU03287 A 20160422

Propriedades químicas

• Peso molecular: 946.7
• Fórmula: C₄₆H₄₄Cl₄N₈O₆
• Cor/forma: Neat
• InChI: InChI=1S/C46H44Cl4N8O6/c1-52-38-26-54-35-21-44(42(62-5)17-29(35)46(38)56-37-23-40(60-3)33(50)19-31(37)48)64-15-7-9-58-12-10-57(11-13-58)8-6-14-63-43-20-34-28(16-41(43)61-4)45(27(24-51)25-53-34)55-36-22-39(59-2)32(49)18-30(36)47/h16-23,25-26H,6-15H2,2-5H3,(H,53,55)(H,54,56)
• SMILES: [C-]#[N+]c1cnc2cc(OCCCN3CCN(CCCOc4cc5ncc(C#N)c(Nc6cc(OC)c(Cl)cc6Cl)c5cc4OC)CC3)c(OC)cc2c1Nc1cc(OC)c(Cl)cc1Cl