2-(2,6-Dichlorophenoxy)-N-phenylacetamide-13C6

CAS: 146607-19-4

Ref. TR-D437054

Informação sobre produto

• Nome: 2-(2,6-Dichlorophenoxy)-N-phenylacetamide-13C6
• Sinónimos: N-((1,2,3,4,5,6-13C6)cyclohexatrienyl)-2-(2,6-dichlorophenoxy)acetamide
• CAS: 146607-19-4

Descrição

Applications 2-(2,6-Dichlorophenoxy)-N-phenylacetamide-13C6 is an intermediate in the synthesis of Diclofenac-13C6 (D436449). Diclofenac-13C6 is a labelled analogue of Diclofenac Acid (D436465), which is a nonsteroidal anti-inflammatory compound and decycloxygenase (COX) inhibitor. Diclofenac-13C6 is also an intermediate in synthesizing Diclofenac-13C6 Sodium Salt (D436453), which is a labelled analogue of Diclofenac Sodium Salt (D436450).
References Yagi, K., et. al.: Biol. Pharm. Bull., 37, 1234 (2014); Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004); Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008); Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009); Kenny, J. R., et al.: J. Med. Chem., 47, 2816 (2004), Sasaki, A., et al.: J. Pharmacol. Sci., 108, 266 (2008); Dalvie, D., et al.: Chem. Res. Toxicol., 22, 357 (2009)

• Marca: TRC

Propriedades químicas

• Peso molecular: 302.105
• Fórmula: C₈C₆H₁₁Cl₂NO₂
• Cor/forma: Neat
• InChI: InChI=1S/C14H11Cl2NO2/c15-11-7-4-8-12(16)14(11)19-9-13(18)17-10-5-2-1-3-6-10/h1-8H,9H2,(H,17,18)/i1+1,2+1,3+1,5+1,6+1,10+1
• Chave InChI: InChIKey=LORXTQPUUJRHAJ-CSPPZNRPSA-N
• SMILES: O=C(COc1c(Cl)cccc1Cl)N[13c]1[13cH][13cH][13cH][13cH][13cH]1