(S)-4,4-Difluoro-N-(3-oxo-1-phenylpropyl)cyclohexanecarboxamide

CAS: 376348-78-6

Ref. TR-D442375

Informação sobre produto

• Nome: (S)-4,4-Difluoro-N-(3-oxo-1-phenylpropyl)cyclohexanecarboxamide
• Sinónimos: Cyclohexanecarboxamide, 4,4-difluoro-N-[(1S)-3-oxo-1-phenylpropyl]-, 4,4-Difluoro-N-[(1S)-3-oxo-1-phenylpropyl]cyclohexanecarboxamide, 4,4-Difluorocyclohexanecarboxylic acid N-((1S)-3-oxo-1-phenylpropyl)amide, UK-453,453, Maraviroc related
• Marca: TRC
• Descrição: Applications (S)-4,4-Difluoro-N-(3-oxo-1-phenylpropyl)cyclohexanecarboxamide acts as a reagent in the synthesis of CCR5 antagonists which are used in HIV therapy and may also be relevant for the treatment of graft-vs.-host disease and Staphylococcus aureus infection.References Asano, S., et al.: ACS Med. Chem. , 5, 133 (2014)

Propriedades químicas

• Peso molecular: 295.32
• Fórmula: C₁₆H₁₉F₂NO₂
• Cor/forma: Neat
• InChI: InChI=1S/C16H19F2NO2/c17-16(18)9-6-13(7-10-16)15(21)19-14(8-11-20)12-4-2-1-3-5-12/h1-5,11,13-14H,6-10H2,(H,19,21)/t14-/m0/s1
• Chave InChI: InChIKey=FCEMFOOGKQYYIR-AWEZNQCLSA-N
• SMILES: O=CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccccc1