N-Des[1-(3-methoxypropyl)-4-piperidinyl] Prucalopride

CAS: 182808-16-8

Ref. TR-D446953

Informação sobre produto

• Nome: N-Des[1-(3-methoxypropyl)-4-piperidinyl] Prucalopride
• Sinónimos: 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxamide
• Marca: TRC

Descrição

Applications N-Des[1-(3-methoxypropyl)-4-piperidinyl] Prucalopride is an impurity of Prucalopride (P838950), a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.
References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008),

Propriedades químicas

• Peso molecular: 212.63
• Fórmula: C₉H₉ClN₂O₂
• Cor/forma: Neat
• InChI: InChI=1S/C9H9ClN2O2/c10-6-3-5(9(12)13)8-4(7(6)11)1-2-14-8/h3H,1-2,11H2,(H2,12,13)
• Chave InChI: InChIKey=PVXPIJICTUHMAO-WJDAMSDJSA-N
• SMILES: [2H]C([2H])(CCCC(=O)OC)C1([2H])SSCC1([2H])[2H]