5,6-Dihydro-5-aza-2’-deoxycytidine (may contain up to 15% inorganics)

CAS: 114522-16-6

Ref. TR-D447775

Informação sobre produto

• Nome: 5,6-Dihydro-5-aza-2’-deoxycytidine (may contain up to 15% inorganics)
• Sinónimos: 4-Amino-1-(2-deoxy-ß-D-erythro-pentofuranosyl)-3,6-dihydro-1,3,5-triazin-2(1H)-one, 2'-Deoxy-5,6-dihydro-5-azacytidine, KP 1212, 6-Amino-3-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,4-dihydro-1,3,5-triazin-2(1H)-one, 4-Amino-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,6-dihydro-1,3,5-triazin-2-one
• CAS: 114522-16-6

Descrição

Applications 5,6-Dihydro-5-aza-2’-deoxycytidine is a selective mutagen that induces A-to-G and G-to-A mutations in the genome of replicating HIV. First-in-class lethal mutagen of HIV-1; Anti-HIV inhibitor.
References Peng, C. S., et al.: Proc. Natl. Acad. Sci. U.S.A., 112, 3229-3234 (2015); Rawson, J. M., et al.: Bioorg. Med. Chem., 21, 7222-7228 (2013); Murakami, E., et al.: Antiviral Res., 67, 10-17 (2005)

• Marca: TRC

Propriedades químicas

• Peso molecular: 230.22
• Fórmula: C₈H₁₄N₄O₄
• Cor/forma: Neat
• InChI: InChI=1S/C8H14N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h4-6,13-14H,1-3H2,(H3,9,10,11,15)/t4-,5+,6+/m0/s1
• Chave InChI: InChIKey=LAOLDMMWVYDDID-KVQBGUIXSA-N
• SMILES: NC1=NC(=O)N([C@H]2C[C@H](O)[C@@H](CO)O2)CN1