N-[(2,4-Difluorophenyl)methyl]-2,4-difluoro-benzenemethanamine

CAS: 1284487-51-9

Ref. TR-D448188

Informação sobre produto

• Nome: N-[(2,4-Difluorophenyl)methyl]-2,4-difluoro-benzenemethanamine
• Sinónimos: 1-(2,4-difluorophenyl)-N-[(2,4-difluorophenyl)methyl]methanamine

Descrição

Applications N-[(2,4-Difluorophenyl)methyl]-2,4-difluoro-benzenemethanamine is derived from 2,4-Difluorobenzylamine (D45085), which acts as a reagent for the design of pyrazole derivatives as non-nucleoside heptatitis B virus inhibitors. It is also used as a reagent in the preparation, HIV antiviral activity, SAR, and molecular modelling of hydroxypyridonecarboxylic acids as HIV reverse transcriptase inhibitors.
References Jia, H., et al.: Eur. J. Med. Chem., 123, 202 (2016); Kankanala, J., et al.: J. Med. Chem., 59, 5051 (2016)

• Marca: TRC

Propriedades químicas

• Peso molecular: 269.238
• Fórmula: C₁₄H₁₁F₄N
• Cor/forma: Neat
• InChI: InChI=1S/C14H11F4N/c15-11-3-1-9(13(17)5-11)7-19-8-10-2-4-12(16)6-14(10)18/h1-6,19H,7-8H2
• Chave InChI: InChIKey=PTAWJKUYGXJHPS-UHFFFAOYSA-N
• SMILES: Fc1ccc(CNCc2ccc(F)cc2F)c(F)c1