1,3-Dihydro-1-(4-piperidinyl)-2H-imidazo[4,5-b]pyridin-2-one Dihydrochloride

CAS: 781649-84-1

Ref. TR-D448735

Informação sobre produto

• Nome: 1,3-Dihydro-1-(4-piperidinyl)-2H-imidazo[4,5-b]pyridin-2-one Dihydrochloride
• Sinónimos: 1-(Piperidin-4-yl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one Dihydrochloride, 1-(Piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one Dihydrochloride, 1-Piperidin-4-yl-1,3-dihydroimidazo[4,5-b]pyridin-2-one Dihydrochloride, 2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine Dihydrochloride, 2-Oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochloride, 1-Piperidin-4-yl-1,3-dihydroimidazo[4,5-b]pyridin-2-one dihydrochloride, 2H-Imidazo[4,5-b]pyridin-2-one, 1,3-dihydro-1-(4-piperidinyl)-, dihydrochloride, 2H-Imidazo[4,5-b]pyridin-2-one, 1,3-dihydro-1-(4-piperidinyl)-, hydrochloride (1:2), 1-(Piperidin-4-yl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one dihydrochloride

Descrição

Applications 1,3-Dihydro-1-(4-piperidinyl)-2H-imidazo[4,5-b]pyridin-2-one is an intermediate used to prepare (3R,6S)-3-amino-6-(2,3-difluorophenyl)azepan-2-one of Telcagepant (MK-0974) for use as a calcitonin gene-related peptide receptor antagonist treating migraine headaches.
References Burgey, C., et al.: Org. Lett., 10, 3235 (2008);

• Marca: TRC

Propriedades químicas

• Peso molecular: 291.18
• Fórmula: C₁₁H₁₆Cl₂N₄O
• Cor/forma: Gray to Dark Gray Solid
• SMILES: CCc1ccc(CCOc2ccc([N+](=O)[O-])cc2)nc1