20β-Dihydrocortisol 21-Acetate

CAS: 66774-49-0

Ref. TR-D448746

Informação sobre produto

• Nome: 20β-Dihydrocortisol 21-Acetate
• Sinónimos: 11beta,17,20beta,21-Tetrahydroxypregn-4-en-3-one 21-Acetate, (11beta,20R)-21-(Acetyloxy)-11,17,20-trihydroxy-pregn-4-en-3-one
• Marca: TRC
• Descrição: Applications 20β-Dihydrocortisol 21-Acetate is an intermediate in the synthesis of 20β-Dihydrocortisol (D448740), which could be used as a potential non invasive diagnostic test of transmissible spongiform encephalopaties. 20β-Dihydrocortisol is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.References Schelcher, F., et. al.: Endocrinology, 140, 2422 (1999); Phillipov, G., et. al.: J. Clin. Endocr. Metab., 81, 3855 (1996); Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol., 296 (2009)

Propriedades químicas

• Peso molecular: 406.51
• Fórmula: C₂₃H₃₄O₆
• Cor/forma: Neat
• InChI: InChI=1S/C23H34O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-20,26-28H,4-9,11-12H2,1-3H3/t16-,17-,18-,19+,20+,21-,22-,23-/m0/s1
• Chave InChI: InChIKey=VUUVQSSKKHJUHI-CGDAUVCTSA-N
• SMILES: CC(=O)OC[C@@H](O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C