Tolterodine-4-methylfumaric Acid Hydrochloride (~80%)

CAS: 1428856-47-6

Ref. TR-D455260

Informação sobre produto

• Nome: Tolterodine-4-methylfumaric Acid Hydrochloride (~80%)
• Sinónimos: 1-[[3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxyphenyl]methyl] Ester (2E)-2-Butenedioic Acid Hydrochloride, Tolterodine-4-methyl-(E)-2-butenedioic Acid Hydrochloride, (R,E)-4-((3-(3-(Diisopropylamino)-1-phenylpropyl)-4-hydroxybenzyl)oxy)-4-oxobut-2-enoic Acid Hydrochloride(~80%)

Descrição

Applications (R,E)-4-((3-(3-(Diisopropylamino)-1-phenylpropyl)-4-hydroxybenzyl)oxy)-4-oxobut-2-enoic Acid is an impurity of Fesoterodine Fumarate (F321300), a muscarinic receptor antagonist for the treatment of Lower Urininary Tract Symptoms (LUTS). It is very similar to Tolterodine (T535800).
References Rogers, D., et al.: Pharmacotherapy, 20, 1092 (2000); Praharaj, S., et al.: J. Psychopharmacology, 19, 426 (2005)

• Marca: TRC

Propriedades químicas

• Peso molecular: 476.0
• Fórmula: C₂₆H₃₄ClNO₅
• Pureza: ~80%
• Cor/forma: Neat
• InChI: InChI=1S/C26H33NO5.ClH/c1-18(2)27(19(3)4)15-14-22(21-8-6-5-7-9-21)23-16-20(10-11-24(23)28)17-32-26(31)13-12-25(29)30;/h5-13,16,18-19,22,28H,14-15,17H2,1-4H3,(H,29,30);1H/b13-12+;/t22-;/m1./s1
• Chave InChI: InChIKey=WDGFCTVEJQLJKJ-WIBFQKCZSA-N
• SMILES: CC(C)N(CC[C@H](c1ccccc1)c1cc(COC(=O)/C=C/C(=O)O)ccc1O)C(C)C.Cl