1-[(4R)-N2-[(10R,12S)-10,12-Dimethyl-1-oxotetradecyl]-4-hydroxy-5-(phenylthio)-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Hydrochloride

CAS: 935739-50-7

Ref. TR-D465745

Informação sobre produto

• Nome: 1-[(4R)-N2-[(10R,12S)-10,12-Dimethyl-1-oxotetradecyl]-4-hydroxy-5-(phenylthio)-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Hydrochloride

Descrição

Applications 1-[(4R)-N2-[(10R,12S)-10,12-Dimethyl-1-oxotetradecyl]-4-hydroxy-5-(phenylthio)-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 is an intermediate in the synthesis of Caspofungin Acetate, an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall.
References Leonard, W. R., et al.: J. Org. Chem., 72, 2335 (2007);

• Marca: TRC

Propriedades químicas

• Peso molecular: 1179.85
• Fórmula: C₅₆H₈₇ClN₈O₁₅S
• Cor/forma: Off-White Solid
• InChI: InChI=1S/C56H86N8O15S.ClH/c1-5-31(2)27-32(3)15-11-8-6-7-9-14-18-43(71)58-38-29-42(70)54(80-37-16-12-10-13-17-37)62-53(77)47-41(69)24-26-63(47)56(79)45(40(68)23-25-57)60-52(76)46(49(73)48(72)34-19-21-35(66)22-20-34)61-51(75)39-28-36(67)30-64(39)55(78)44(33(4)65)59-50(38)74;/h10,12-13,16-17,19-22,31-33,36,38-42,44-49,54,65-70,72-73H,5-9,11,14-15,18,23-30,57H2,1-4H3,(H,58,71)(H,59,74)(H,60,76)(H,61,75)(H,62,77);1H/t31-,32+,33+,36+,38-,39-,40+,41-,42+,44-,45-,46-,47-,48-,49-,54?;/m0./s1