7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin
CAS: 76877-33-3
Ref. TR-D473778
5mg | 212,00 € | ||
10mg | 343,00 € | ||
25mg | 619,00 € |
Informação sobre produto
- 1-[4-[7-(Diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl]phenyl]-1H-pyrrole-2,5-dione
- 7-(Diethylamino)-3-(4'-maleimidylphenyl)-4-methylcoumarin
- D 346
- 3-(4-Maleimidophenyl)-4-methyl-7-(diethylamino)coumarin
Applications 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin is a thiol-reactive fluorescent probe. 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin (CPM) is a thiol-reactive fluorescent probe. CPM selectively forms Michael adducts in the presence of hyperreactive sulfhydryls. CPM has been used to monitor the release of thiols, quantitate thiol in microplate reactions, and to distinguish proliferating cancer cells by nucleolar protein staining. Dyes and metabolites.
References 1. Sippel, T.O. 1981. J. Histochem. Cytochem. 29: 1377-1381. PMID: 73204962. Liu, G., et al. 1994. J. Biol. Chem. 269: 33028-33034. PMID: 78065313. Liu, G., et al. 1994. Mol. Pharmacol. 45: 189-200. PMID: 81146704. Feng, W., et al. 1999. Mol. Pharmacol. 55: 821-831. PMID: 102205605. Han, M.S., et al. 2004. J. Org. Chem. 69: 2853-2855. PMID: 150749386. Ptak, C.P., et al. 2005. Biochemistry. 44: 62-71. PMID: 156288467. Khersonsky, O., et al. 2006. Chembiochem. 7: 49-53. PMID: 16329153
Propriedades químicas
Consulta técnica sobre: TR-D473778 7-Diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin
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