16-epi Mometasone Furoate

CAS: 2231764-75-1

Ref. TR-D474688

Informação sobre produto

• Nome: 16-epi Mometasone Furoate
• Sinónimos: 9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione, Mometasone Impurity S, Pregna-1,4-diene-3,20-dione, 9,21-dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-, (11ß,16ß)-, 9,21-Dichloro-11ß-hydroxy-16ß-methyl-3,20-dioxopregna-1,4-dien-17-yl Furan-2-carboxylate, Mometasone Furoate Imp. S (EP)
• CAS: 2231764-75-1

Descrição

Applications 9,​21-Dichloro-​17-​[(2-​furanylcarbonyl)​oxy]​-​11-​hydroxy-​16-​methylpregna-​1,​4-​diene-​3,​20-​dione is an impurity of Mometasone (M490000), a topical corticosteroid used as an anti-inflammatory.
References Shapiro, E.L., et al.: J. Med. Chem., 30, 1581 (1987), Graft, D., et al.: J. Allergy Clin. Immunol., 98, 724 (1996)

• Marca: TRC

Propriedades químicas

• Peso molecular: 521.43
• Fórmula: C₂₇H₃₀Cl₂O₆
• Cor/forma: Neat
• InChI: InChI=1S/C27H30Cl2O6/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,22(32)14-28)35-23(33)20-5-4-10-34-20/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3/t15-,18-,19-,21-,24-,25-,26-,27-/m0/s1
• Chave InChI: InChIKey=WOFMFGQZHJDGCX-NSXGOKPNSA-N
• SMILES: C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)c1ccco1)C(=O)CCl