N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(4-methoxyphenoxy)propyl]-1-piperazineacetamide

CAS: 1393717-45-7

Ref. TR-D476765

Informação sobre produto

• Nome: N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(4-methoxyphenoxy)propyl]-1-piperazineacetamide
• Sinónimos: 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(4-methoxyphenoxy)propyl]-, N-(2,6-Dimethylphenyl)-2-{4-[2-hydroxy-3-(4-methoxyphenoxy)propyl]piperazin-1-y
• CAS: 1393717-45-7

Descrição

Applications N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(4-methoxyphenoxy)propyl]-1-piperazineacetamide is an impurity of the drug Ranolazine (R122500). Ranolazine is an anti-ischemic agent which modulates myocardial metabolism and it is an antianginal.
References Chaitman, B.R., et al.: J. Am. Coll. Cardial., 43, 1375 (2004), McCormack, J.G., et al.: Gen. Pharmacol., 30, 639 (1998), Schofield, J.A.H., et al.: Expert Opin. Invest. Drugs, 11, 117 (2002)

• Marca: TRC

Propriedades químicas

• Peso molecular: 427.536
• Fórmula: C₂₄H₃₃N₃O₄
• Cor/forma: Neat
• InChI: InChI=1S/C24H33N3O4/c1-18-5-4-6-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-9-7-21(30-3)8-10-22/h4-10,20,28H,11-17H2,1-3H3,(H,25,29)
• Chave InChI: InChIKey=YCRVPHYZFCHTNN-UHFFFAOYSA-N
• SMILES: COc1ccc(OCC(O)CN2CCN(CC(=O)Nc3c(C)cccc3C)CC2)cc1