Informação sobre produto
- (2-Oxopropyl)phosphonic Acid Dimethyl Ester
- (Dimethylphosphono)acetone
- (2-Oxopropyl)phosphonic acid dimethyl ester
- 1-Dimethoxyphosphorylpropan-2-one
- Acetylmethylphosphonic acid dimethyl ester~Dimethyl acetonylphosphonate~Dimethyl (2-oxopropyl)phosphonate
- Dimethyl 2-oxopropanephosphonate
- Dimethyl 2-oxopropylphosphonate
- Dimethyl P-(2-oxopropyl)phosphonate
- Dimethyl acetonylphosphonate
- Dimethyl acetylmethylphosphonate
- Ver mais sinónimos
- Dimethyl β-keto-propylphosphonate
- Phosphonic acid, (2-oxopropyl)-, dimethyl ester
- Phosphonic acid, P-(2-oxopropyl)-, dimethyl ester
- Phosphonic acid, acetonyl-, dimethyl ester
Applications Dimethyl (2-Oxopropyl)phosphonate is a common chemical reagent used in the synthesis of pharmaceuticals. Used in the synthesis of phenyl-substituted prostaglandins used as selective antiglaucoma agents. Also used in the synthesis of dipeptidyl enoates as potent rhodesain inhibitors. Rhodesain is the cysteine protease of Trypanosoma brucei parasites which cause African sleeping sickness.
References Resul, B. et al.: J. Med. Chem., 36, 243 (1993); Ehmke, V. et al.: ChemMedChem., 8, 965 (2013);
Propriedades químicas
Consulta técnica sobre: TR-D476790 Dimethyl (2-Oxopropyl)phosphonate
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