2,5-Dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one-d3

Ref. TR-D480167

Informação sobre produto

• Nome: 2,5-Dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one-d3
• Sinónimos: 5-methyl-2-(trideuteriomethyl)-3,4-dihydropyrido[4,3-b]indol-1-one

Descrição

Applications 2,5-Dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one-d3 is the deuterated version of 2,5-Dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one (D480165), which is an impurity of Alosetron (A575500) that is a serotonin 5HT3 receptor antagonist, used in treatment of irritable bowel syndrome.
References Camilleri, M., et al.: Lancet, 355, 1035 (2000); Nestorov, I., et al.: Drug Metab. Dispos., 30, 276 (2002); Lewis, D., et al.: Drug Metab. Rev., 35, 1 (2003); Tang, H., et al.: J. Pharm. Sci., 95, 1783 (2006); Gleeson, M., et al.: J. Med. Chem., 50, 101 (2007);

• Marca: TRC

Propriedades químicas

• Peso molecular: 217.282
• Fórmula: C₁₃D₃H₁₁N₂O
• Cor/forma: Neat
• InChI: InChI=1S/C13H14N2O/c1-14-8-7-11-12(13(14)16)9-5-3-4-6-10(9)15(11)2/h3-6H,7-8H2,1-2H3/i1D3
• Chave InChI: InChIKey=XXBITUHGHVPSAB-FIBGUPNXSA-N
• SMILES: [2H]C([2H])([2H])N1CCc2c(c3ccccc3n2C)C1=O