Dioscin

CAS: 19057-60-4

Ref. TR-D485230

Informação sobre produto

• Nome: Dioscin
• Sinónimos: 3-O-ß-D-a-L-Rhamnopyranosyl(1?4)-[a-L-rhamnopyranosyl(1?2)]-ß-D-glucopyranoside-diosgenin, Collettiside III, Dioscine, Diosgenin 3-O-a-L-Rhamnopyranosyl-(1?2)-[a-L-rhamnopyranosyl-(1?4)]-ß-D-glucopyranoside, Diosgenin 3-O-a-L-Rhamnopyranosyl-(1?4)-[a-L-rhamnopyranosyl-(1?2)]-ß-D-glucopyranoside, Diosgenin bis-a-L-rhamnopyranosyl-(1?2 and 1?4)-ß-D-glucopyranoside, Paris III, Polyphyllin III, (3ß,25R)-Spirost-5-en-3-yl O-6-deoxy-a-L-mannopyranosyl-(1?2)-O-[6-deoxy-a-L-mannopyranosyl-(1?4)]-ß-D-glucopyranoside, (3beta,14xi,25R)-spirost-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[6-deoxy-alpha-L-mannopyranosyl-(1->4)]-beta-D-glucopyranoside, (3beta,25R)-spirost-5-en-3-yl 6-deoxy-alpha-L-mannopyranosyl-(1->2)-[6-deoxy-alpha-L-mannopyranosyl-(1->4)]-beta-D-glucopyranoside, (3β,25R)-Spirost-5-en-3-yl O-6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl-(1→2)-O-[6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→4)]-β-<smallcap>D</span>-glucopyranoside, 3-O-β-<span class="text-smallcaps">D</smallcap>-α-<smallcap>L</smallcap>-Rhamnopyranosyl(1→4)-[α-<smallcap>L</smallcap>-rhamnopyranosyl(1→2)]-β-<smallcap>D</span>-glucopyranoside-diosgenin, Beta-D-Glucopyranoside,(3-Beta,25R)-Spirost-5-En-3-Ylo-6-Deoxy-Alpha-L-Mannop, Collettisideiii, Dioscin(P), Diosgenin 3-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→2)-[α-<smallcap>L</smallcap>-rhamnopyranosyl-(1→4)]-β-<smallcap>D</span>-glucopyranoside, Diosgenin 3-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→4)-[α-<smallcap>L</smallcap>-rhamnopyranosyl-(1→2)]-β-<smallcap>D</span>-glucopyranoside, Diosgenin bis-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→2 and 1→4)-β-<smallcap>D</span>-glucopyranoside, Parissaponin III, Yranosyl-(1-2)-O-(6-Deoxy-Alpha-L-Mannopyranosyl)-(1-4))-, β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→2)-O-[6-deoxy-α-<smallcap>L</span>-mannopyranosyl-(1→4)]-, β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-

Descrição

Applications Dioscin, a natural steroid saponin that has been shown to promote anticancer activity against several forms of cancers. Dioscin induces cancer cell apoptosis through elevated oxidative stress mediated by downregulation of peroxiredoxins.
References Wang, Z., et al.: Land. Biosci., 13, 138 (2012); Shah, H.J., et al.: J. Anal. BIoanal. Tech., 3, 141 (2012); Zhao, X.M., et al.: Toxiciol. Lett., 214, 69 (2012);

• Marca: TRC

Propriedades químicas

• Peso molecular: 869.04
• Fórmula: C₄₅H₇₂O₁₆
• Cor/forma: Neat
• InChI: InChI=1S/C45H72O16/c1-19-9-14-45(54-18-19)20(2)30-28(61-45)16-27-25-8-7-23-15-24(10-12-43(23,5)26(25)11-13-44(27,30)6)57-42-39(60-41-36(52)34(50)32(48)22(4)56-41)37(53)38(29(17-46)58-42)59-40-35(51)33(49)31(47)21(3)55-40/h7,19-22,24-42,46-53H,8-18H2,1-6H3/t19-,20+,21+,22+,24+,25-,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36-,37+,38-,39-,40+,41+,42-,43+,44+,45-/m1/s1