N-(Diphenylmethylene)glycine Benzyl Ester

CAS: 81477-91-0

Ref. TR-D492185

Informação sobre produto

• Nome: N-(Diphenylmethylene)glycine Benzyl Ester
• Sinónimos: N-(Diphenylmethylene)glycine Phenylmethyl Ester, (Benzhydrylideneamino)acetic Acid Benzyl Ester, Benzyl 2-((Diphenylmethylene)amino)acetate, Diphenylmethylene-Glycine benzyl ester, DPM-Gly-OBzl, benzyl N-(diphenylmethylidene)glycinate

Descrição

Applications N-(Diphenylmethylene)glycine benzyl ester is used as a reagent to synthesize (-)-Lepadiformine, a marine cytotoxic alkaloid that exhibits activity towards lunch carcinoma cell lines. N-(Diphenylmethylene)glycine benzyl ester is also used as a reagent to prepare (+)-Cylindricine C, a marine alkaloid that also shows activity against tumour cell lines.
References Biard, J., et al.: Tetrahedron Lett., 35, 2691 (1994); Caldwell, J. & Craig, D.: Angew. Chem. Int. Edit., 46, 2631 (2007); Mihara, H., et al.: Heterocycles, 72, 421 (2007)

• Marca: TRC

Propriedades químicas

• Peso molecular: 329.39
• Fórmula: C₂₂H₁₉NO₂
• Cor/forma: White to Off-White Solid
• InChI: InChI=1S/C22H19NO2/c24-21(25-17-18-10-4-1-5-11-18)16-23-22(19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15H,16-17H2
• Chave InChI: InChIKey=KFNIDRLZPBRDNJ-UHFFFAOYSA-N
• SMILES: O=C(CN=C(c1ccccc1)c1ccccc1)OCc1ccccc1