Dipyrone-d3

CAS: 68-89-3

Ref. TR-D492862

Informação sobre produto

• Nome: Dipyrone-d3
• Sinónimos: 1-[(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonic Acid-d3 Sodium Salt, (Antipyrinylmethylamino)methanesulfonic Acid-d3 Sodium Salt, ARPF-d3, Algocalmin-d3, Algopyrin-d3, Anador-d3, Analgin-d3, Analgine-d3, Andolor-d3, Conmel-d3, Diprofarn-d3, Gifaril-d3, Lisador-d3, Metamizol-d3, Metamizole-d3, Metamizole Sodium-d3, Metamizole Sodium Salt-d3, Metapyrin-d3, Methamizole-d3 Sodium, Methampyrone-d3, Methylmelubrin-d3, Metilon-d3, Narone-d3, Sulpin-d3, Sulpyrin-d3, Sulpyrine-d3, Algocalmin, Algopyrin, Amoloid HV, Amoloid LV, Anador, Analgin, Analgin DAB10, Analgine, Andolor, Arpf, Collatex A/RE, Collatex Arm Extra, CollatexA/RE Extra, Conmel, Diprofarn, Dipyrone,hydrate, Duckammon, E 403, Gifaril, Kimica Algin NH, Kimitsu Algin NH, Lisador, Manutex PC-MV, Metamizol, Metamizole, Metamizole Sodium, Metamizole sodium salt, Metapyrin, Methamizole sodium, Methampyrone, Methanesulfonic acid, (antipyrinylmethylamino)-, sodium salt, Methanesulfonic acid, 1-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt (1:1), Methanesulfonic acid, [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt, Methylmelubrin, Metilon, Narone, Natrium-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methansulfonat, Neo-melubrine, Noramidopyrine methanesulfonate sodium, Noramidopyrine methanesulfonate sodium salt, Noraminophenazone methanesulfonate sodium salt, Noraminophenazone sodium mesylate, Novalgetol, Novalgin, Novamidazophen, Novaminophenazone, Novaminsulfone, Novaminsulfone sodium, Novaminsulfonium, Novaminsulfonum, Noveltex, Optalgin, Pharmalgine, Protamon S, Pyralgine, Pyretin, Pyretin (pharmaceutical), Restriva, Sodium ((2,3-Dihydro-1,5-Dimethyl-3-Oxo-2-Phenyl-1H-Pyrazol-4-Yl)Methylamino)Methanesulfonate, Sodium (antipyrinylmethylamino)methanesulfonate, Sodium 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonate, Sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonate, Sodium metamizole, Sodium noramidopyrine methanesulfonate, Sodium novaminsulfonate, Sulpin, Sulpyrin, Sulpyrine, [(1,5-Dimethyl-3-Oxo-2-Phenyl-Pyrazolidin-4-Yl)-Methyl-Amino]Methylsulfonyloxy Sodium, [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate, [(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonic acid sodium salt, [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazole-4-yl)methylamino]methanesulfonate de sodium, [(2-fenil-2,3-dihidro-1,5-dimetil-3-oxo-1H-pirazol-4-il)metilamino]metanosulfonato de sodio, sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate, sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate hydrate (1:1:1)

Descrição

Stability Hygroscopic
Applications Labelled Dipyrone. Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models.
References Reith, J. et al.: Lancet, 347, 422 (1996); Grau, A. et al.: J. Neurol. Sci., 171, 115 (1999); Schwarz, S. et al.: Neurology, 2000, 54, 354 (2000); Greer, D. et al.: Stroke, 39, 3029 (2008);

• Marca: TRC

Propriedades químicas

• Peso molecular: 336.36
• Fórmula: C₁₃H₁₃D₃N₃NaO₄S
• Cor/forma: Off-White
• InChI: InChI=1S/C13H17N3O4S.Na/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;/h4-8H,9H2,1-3H3,(H,18,19,20);/q;+1/p-1/i2D3
• Chave InChI: InChIKey=DJGAAPFSPWAYTJ-MUTAZJQDSA-M
• SMILES: [2H]C([2H])([2H])N(CS(=O)(=O)O[Na])c1c(C)n(C)n(-c2ccccc2)c1=O