5Beta,10Beta-Epoxy-3,3-ethylenedioxy-17Beta-hydroxy-17Alpha-(prop-1-ynyl)estr-9(11)-ene

CAS: 162681-70-1

Ref. TR-E162680

Informação sobre produto

• Nome: 5Beta,10Beta-Epoxy-3,3-ethylenedioxy-17Beta-hydroxy-17Alpha-(prop-1-ynyl)estr-9(11)-ene
• Sinónimos: 5beta,10beta-Epoxy-3,3-(ethylenedioxy)-17beta-hydroxy-3-oxo-17alpha-(1-propynyl)estr-9(11)-ene
• Marca: TRC

Descrição

Applications 5β,10β-Epoxy-3,3-ethylenedioxy-17β-hydroxy-17α-(prop-1-ynyl)estr-9(11)-ene is an intermediate in the synthesis of 11-ent-Mifepristone (M343980), which is an enantiomic impurity of Mifepristone (M343975), a progesterone receptor antagonist with partial agonist activity.
References Healy, D.L., et al.: J. Clin. Endocrinol. Metab., 57, 863 (1983), Rauch, M., et al.: Eur. J. Biochem., 148, 213 (1985), Baulieu, E.E., et al.: Science, 245, 1351 (1989), Brogden, R.N., et al.: Drugs, 45, 384 (1993)

Propriedades químicas

• Peso molecular: 370.48
• Fórmula: C₂₃H₃₀O₄
• Cor/forma: White
• SMILES: CC#C[C@]1(O)CC[C@H]2[C@@H]3CC[C@]45CC6(CC[C@]4(O5)C3=CC[C@@]21C)OCCO6