4-[(E)-(1-methyl-4-piperidyl)iminomethyl]phenol

CAS: 706779-91-1

Ref. TR-E521543

Informação sobre produto

• Nome: 4-[(E)-(1-methyl-4-piperidyl)iminomethyl]phenol
• Sinónimos: 4-[(Z)-(1-methylpiperidin-4-yl)iminomethyl]phenol, 1-(4-Fluorobenzyl)-1-(1-Methylpiperidin-4-Yl)-3-[4-(2-Methylpropoxy)Benzyl]Urea, 1-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea, 1-[(4-Fluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea, N-(4-Fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-[[4-(2-methylpropyloxy)phenyl]methyl]carbamide, N-[(4-Fluorophenyl)methyl]-N-(1-methyl-4-piperidinyl)-N′-[[4-(2-methylpropoxy)phenyl]methyl]urea, Nuplazid, Urea, N-[(4-fluorophenyl)methyl]-N-(1-methyl-4-piperidinyl)-N′-[[4-(2-methylpropoxy)phenyl]methyl]-

Descrição

Applications 4-[(E)-(1-methyl-4-piperidyl)iminomethyl]phenol is an impurity of Pimavanserin (P441800), which is a drug used in the treatment of Parkinson’s disease and psychosis.
References Snigdha, S., et al.: J. Pharmacol. Exper. Ther., 332, 622 (2010), Meltzer, H., et al.: Neuropsychopharmacol., 35, 881 (2010)

• Marca: TRC

Propriedades químicas

• Peso molecular: 218.295
• Fórmula: C₁₃H₁₈N₂O
• Cor/forma: Neat
• InChI: InChI=1S/C13H18N2O/c1-15-8-6-12(7-9-15)14-10-11-2-4-13(16)5-3-11/h2-5,10,12,16H,6-9H2,1H3/b14-10-
• Chave InChI: InChIKey=LFVYFLAEZMHTQT-UVTDQMKNSA-N
• SMILES: CN1CCC(/N=C\c2ccc(O)cc2)CC1