14,15-Epoxyeicosatrienoic Acid

CAS: 197508-62-6

Ref. TR-E589138

Informação sobre produto

• Nome: 14,15-Epoxyeicosatrienoic Acid
• Sinónimos: (5Z,8Z,11Z)-13-(3-Pentyl-2-oxiranyl)-5,8,11-tridecatrienoic Acid, 14(15)-EET, 14(15)-Epoxy-5Z,8Z,11Z-eicosatrienoic Acid, (all-Z)-13-(3-Pentyloxiranyl)-5,8,11-tridecatrienoic Acid
• Marca: TRC

Descrição

Applications Epoxyeicosatrienoic Acid (EET) has antihypertensive and anti-inflammatory properties and play a role in the maintenance of renal vascular function. N,​N'-​dicyclohexylurea (DCU) increased release of 14,15-EET when the cells were stimulated with a calcium ionophore.Also, it is derived from Arachidonic Acid >97% (A765000), which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides.
References Zhao, X., et al.: J. Am. Soc. Nephrol., 15, 1244 (2004); Fang, X., et al.: J. Biol. Chem., 276, 14867 (2001); Kurosawa, T., et al.: J. Cell. Physiol., 219, 606 (2009); Mazalli, M., et al.: J. Agric. Food Chem., 57, 5028 (2009);

Propriedades químicas

• Peso molecular: 320.466
• Fórmula: C₂₀H₃₂O₃
• Cor/forma: Neat
• InChI: InChI=1S/C20H32O3/c1-2-3-12-15-18-19(23-18)16-13-10-8-6-4-5-7-9-11-14-17-20(21)22/h4,6-7,9-10,13,18-19H,2-3,5,8,11-12,14-17H2,1H3,(H,21,22)/b6-4-,9-7-,13-10-
• Chave InChI: InChIKey=JBSCUHKPLGKXKH-ILYOTBPNSA-N
• SMILES: CCCCCC1OC1C/C=C\C/C=C\C/C=C\CCCC(=O)O