Erlotinib Hydrochloride (Tarceva)

CAS: 183319-69-9

Ref. TR-E625000

Informação sobre produto

• Nome: Erlotinib Hydrochloride (Tarceva)
• Sinónimos: OSI 774, Tarceva,N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-Quinazolinamine, 6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride, [6,7-Bis(2-methoxyethoxy)quinazolin-4-yl]-(3-ethynylphenyl)amine hydrochloride, N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Hydrochloride, CP 358774, Erlotinib hydrochloride, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-Quinazolinamine, 6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride, 4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-, hydrochloride (1:1), 4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-, monohydrochloride, Cp 358774, Erlotinib HCl, Erlotinib Hcl Salt, Erlotinib, Hydrochloride Salt, Erlotinib, OS-774, N-(2-chloro-6-methyl-phenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methyl-pyrimidin-4-yl]amino]thiazole-5-carboxamide, N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4- Hydrochloride, N-(3-Ethynylphenyl)-6,7-bis-(2-methoxyethoxy)-quinazolin-4-amine Hydrochloride, N-(3-Ethynylphenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine hydrochloride, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride (1:1), N-(4-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride (1:1), Osi 774, Tarceva, [6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4yl]-(3-ethynyl-phenyl)-amine, quinazolinamine, Hydrochloride Salt, OSI 774, Tarceva

Descrição

Applications Selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor. Antineoplastic.
References Moyer, J.D., et al.: Cancer Res., 57, 4838 (1997), Hidalgo, M., et al.: J. Clin. Oncol., 19, 3267 (2001), Perez-Soler, R., et al.: J. Clin. Oncol., 22, 3238 (2004), Blackhall, F.H., et al.: Expert Opin. Pharmacother., 6, 995 (2005),

• Marca: TRC

Propriedades químicas

• Peso molecular: 429.90
• Fórmula: C₂₂H₂₃N₃O₄·ClH
• Cor/forma: White To Light Yellow
• InChI: InChI=1S/C22H23N3O4.ClH/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22, /h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25), 1H
• Chave InChI: InChIKey=VNWKTOKETHGBQD-UHFFFAOYSA-N
• SMILES: C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1.Cl