Estradiol 6-N3-Adenine (~90%)

Ref. TR-E668590

Informação sobre produto

• Nome: Estradiol 6-N3-Adenine (~90%)
• Sinónimos: (8R,9S,13S,14S,17S)-6-(6-Amino-3H-purin-3-yl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
• Marca: TRC
• Descrição: Applications Estradiol 6-N3-Adenine is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogeneous initiators of various human cancers, such as breast & prostate.References Yang, L., et al.: Prostate, 69, 41 (2009); Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006); Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)

Propriedades químicas

• Peso molecular: 405.493
• Fórmula: C₂₃H₂₇N₅O₂
• Pureza: ~90%
• Cor/forma: Neat
• InChI: InChI=1S/C23H27N5O2/c1-23-7-6-14-13-3-2-12(29)8-16(13)18(9-15(14)17(23)4-5-19(23)30)28-11-27-21(24)20-22(28)26-10-25-20/h2-3,8,10-11,14-15,17-19,29-30H,4-7,9,24H2,1H3/t14-,15-,17+,18?,19+,23+/m1/s1
• Chave InChI: InChIKey=ABUVIBYOTRBZKW-WPVFROKISA-N
• SMILES: C[C@]12CC[C@@H]3c4ccc(O)cc4C(n4cnc(N)c5ncnc4-5)C[C@H]3[C@@H]1CC[C@@H]2O