Desmethyl-O-Benzyl Apixaban Carboxylate

CAS: 1620494-29-2

Ref. TR-E702870

Informação sobre produto

• Nome: Desmethyl-O-Benzyl Apixaban Carboxylate
• Sinónimos: ethyl 7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-1-(4-phenylmethoxyphenyl)-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate

Descrição

Applications Apixaban(A726700) Impurity. Apixaben is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation. Apixaban Impurity.
References Luettgen, J.M., et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T., et al.: J. Thromb. Thrombol., 31, 310 (2011); Barrett, Y.C., et al.: Thromb. Haemos., 105, 181 (2011);

• Marca: TRC

Propriedades químicas

• Peso molecular: 564.631
• Fórmula: C₃₃H₃₂N₄O₅
• Cor/forma: Neat
• InChI: InChI=1S/C33H32N4O5/c1-2-41-33(40)30-28-19-21-36(25-13-11-24(12-14-25)35-20-7-6-10-29(35)38)32(39)31(28)37(34-30)26-15-17-27(18-16-26)42-22-23-8-4-3-5-9-23/h3-5,8-9,11-18H,2,6-7,10,19-22H2,1H3
• Chave InChI: InChIKey=NQADJRHKQGNFII-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1nn(-c2ccc(OCc3ccccc3)cc2)c2c1CCN(c1ccc(N3CCCCC3=O)cc1)C2=O