2-(Ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol-d5

CAS: 2252319-75-6

Ref. TR-E892962

Informação sobre produto

• Nome: 2-(Ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol-d5
• Sinónimos: 1-(2-(Ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol-d5
• Marca: TRC
• Descrição: Applications 2-(Ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol-d5 is an intermediate in synthesizing Resiquimod-d5 (R144682), an isotope labelled Resiquimod (R144680) which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.References Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008)

Propriedades químicas

• Peso molecular: 304.4
• Fórmula: C₁₇H₁₆D₅N₃O₂
• Cor/forma: Neat
• InChI: InChI=1S/C17H21N3O2/c1-4-22-10-15-19-14-9-18-13-8-6-5-7-12(13)16(14)20(15)11-17(2,3)21/h5-9,21H,4,10-11H2,1-3H3/i1D3,4D2
• Chave InChI: InChIKey=SESDEFPIFUOEIX-UFWAFWIVSA-N
• SMILES: CC(=O)O[C@H]1C(=O)[C@]2(C)[C@@H](O)C[C@H]3OC[C@@]3(OC(C)=O)[C@H]2[C@H](OC(=O)c2ccccc2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)/C=C/c3ccccc3)c3ccccc3)C(C)=C1C2(C)C