Ethyl 5-Chloro-2-(((trifluoromethyl)sulfonyl)oxy)-1H-indole-1-carboxylate

Ref. TR-E901798

Informação sobre produto

• Nome: Ethyl 5-Chloro-2-(((trifluoromethyl)sulfonyl)oxy)-1H-indole-1-carboxylate

Descrição

Applications Ethyl 5-Chloro-2-(((trifluoromethyl)sulfonyl)oxy)-1H-indole-1-carboxylate is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3β inhibitors as anticancer agents.
References Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012);

• Marca: TRC

Propriedades químicas

• Peso molecular: 371.717
• Fórmula: C₁₂H₉ClF₃NO₅S
• Cor/forma: Light Brown Solid
• InChI: InChI=1S/C12H9ClF3NO5S/c1-2-21-11(18)17-9-4-3-8(13)5-7(9)6-10(17)22-23(19,20)12(14,15)16/h3-6H,2H2,1H3
• Chave InChI: InChIKey=ZUGRJSVKQAXFFK-UHFFFAOYSA-N
• SMILES: CCOC(=O)n1c(OS(=O)(=O)C(F)(F)F)cc2cc(Cl)ccc21