4,6-O-Ethylidene-D-glucose

CAS: 18465-50-4

Ref. TR-E919775

Informação sobre produto

• Nome: 4,6-O-Ethylidene-D-glucose
• Sinónimos: Pyrano[3,2-d]-1,3-dioxin D-glucopyranose Derivative, 4,6-O-Ethylidene-D-glucopyranose, (2R,4aR,7R,8R,8aS)-2-Methylhexahydropyrano[3,2-d][1,3]dioxine-6,7,8-triol, 4,6-O-Ethylidene-D-glucopyranoside, (1R,2S,3R,6R)-9-methyl-5,8,10-trioxabicyclo[4.4.0]decane-2,3,4-triol

Descrição

Applications 4,6-O-Ethylidene-D-glucose is an intermediate in synthesizing α-Etoposide (E933745), which is a cytotoxic agent (anticancer drug), which belongs to the drug type topoisomerase inhibitor. It is also an antineoplastic drug.
References Burden, D.A., et al.: J. Biol. Chem., 271, 29238 (1996;, Joel, S., et al.: Cancer Treat. Rev., 22, 179 (1996); Xuan, T., et al.: Chemical Research in Chinese Universities, 11, 79 (1995);

• Marca: TRC

Propriedades químicas

• Peso molecular: 206.19
• Fórmula: C₈H₁₄O₆
• Cor/forma: White Fine Crystalline Solid
• InChI: InChI=1S/C8H14O6/c1-3-12-2-4-7(13-3)5(9)6(10)8(11)14-4/h3-11H,2H2,1H3/t3?,4-,5-,6-,7-,8?/m1/s1
• Chave InChI: InChIKey=VZPBLPQAMPVTFO-DBVAJOADSA-N
• SMILES: CC1OC[C@H]2OC(O)[C@H](O)[C@@H](O)[C@@H]2O1