Etoposide Phosphate Diammonium Salt

CAS: 117091-64-2

Ref. TR-E933755

Informação sobre produto

• Nome: Etoposide Phosphate Diammonium Salt
• Sinónimos: [5R-[5α,5aβ,8aα,9β(R*)]]-5-[3,5-Dimethoxy-4-(phosphonooxy)phenyl]-9-[(4,6-O-ethylidene-β-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, BMY 40481, Etopofos, Etopophos, Etoposide 4'-Phosphate, (5R,5aR,8aR,9S)-5-[3,5-Dimethoxy-4-(phosphonooxy)phenyl]-9-[[4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
• Marca: TRC
• Descrição: Applications A bioequivalent prodrug of the DNA topoisomerase II inhibitor Etoposide (E933750). Antineoplastic used in the treatment of a wide variety of hematological malignancies and solid tumors.References Kaul, S. et al.: J. Clin. Pharmacol., 13, 2835 (1995); J. Pharmakin. Biopharmac., 24, 313 (1996); Brooks, D.J. et al.: Anti-Cancer Drugs, 6, 637 (1995)

Propriedades químicas

• Peso molecular: 668.54 + 2(34.06)
• Fórmula: C₂₉H₃₁O₁₆P•2NH₄
• Cor/forma: Neat
• InChI: InChI=1S/C29H33O16P.2H3N/c1-11-38-9-20-27(42-11)23(30)24(31)29(43-20)44-25-14-7-17-16(40-10-41-17)6-13(14)21(22-15(25)8-39-28(22)32)12-4-18(36-2)26(19(5-12)37-3)45-46(33,34)35;;/h4-7,11,15,20-25,27,29-31H,8-10H2,1-3H3,(H2,33,34,35);2*1H3/t11-,15+,20-,21-,22+,23-,24-,25-,27-,29+;;/m1../s1
• Chave InChI: InChIKey=LIQODXNTTZAGID-OCBXBXKTSA-N
• SMILES: COc1cc([C@@H]2c3cc4c(cc3[C@@H](O[C@@H]3O[C@@H]5CO[C@@H](C)O[C@H]5[C@H](O)[C@H]3O)[C@H]3COC(=O)[C@H]23)OCO4)cc(OC)c1OP(=O)(O)O