Febuxostat

CAS: 144060-53-7

Ref. TR-F229000

Informação sobre produto

• Nome: Febuxostat
• Sinónimos: 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic acid, 2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid, FBX, Febugood, Feburic, Febutaz, TEI 6720, TMX 67, Uloric, Zurig
• Marca: TRC
• Descrição: Applications Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),

Propriedades químicas

• Peso molecular: 316.37
• Fórmula: C₁₆H₁₆N₂O₃S
• Cor/forma: White To Off-White
• InChI: InChI=1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)
• Chave InChI: InChIKey=OBZKXMLNDVHGIK-UHFFFAOYSA-N
• SMILES: Cc1nc(-c2ccc(OCC(C)C)c(C#N)c2)sc1C(=O)O