FK866

CAS: 658084-64-1

Ref. TR-F370030

Informação sobre produto

• Nome: FK866
• Sinónimos: (2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide, APO 866, K 22.175, 2-Propenamide, N-[4-(1-benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-, (2E)-, Apo 866, Apo866, Fk 866, Fk866
• CAS: 658084-64-1

Descrição

Applications FK866 is a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase), that induces tumor cell apoptosis, and thus is a potential anticancer drug.
References Hasmann, M., Schemainda, I.: Cancer Res., 63, 7436 (2003); Khan, J., et a.: Nat. Struct. Mol. Biol., 13, 582 (2006);

• Marca: TRC

Propriedades químicas

• Peso molecular: 391.51
• Fórmula: C₂₄H₂₉N₃O₂
• Cor/forma: Neat
• InChI: InChI=1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3,6,8-12,15,19-20H,4-5,7,13-14,16-18H2,(H,26,28)/b12-11+
• Chave InChI: InChIKey=KPBNHDGDUADAGP-VAWYXSNFSA-N
• SMILES: O=C(/C=C/c1cccnc1)NCCCCC1CCN(C(=O)c2ccccc2)CC1