N-Formyl Apixaban

CAS: 1351611-14-7

Ref. TR-F696855

Informação sobre produto

• Nome: N-Formyl Apixaban
• Sinónimos: N-Formyl-4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide

Descrição

Applications N-Formyl Apixaban is derived from Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);

• Marca: TRC

Propriedades químicas

• Peso molecular: 487.51
• Fórmula: C₂₆H₂₅N₅O₅
• Cor/forma: Neat
• InChI: InChI=1S/C26H25N5O5/c1-36-20-11-9-19(10-12-20)31-24-21(23(28-31)25(34)27-16-32)13-15-30(26(24)35)18-7-5-17(6-8-18)29-14-3-2-4-22(29)33/h5-12,16H,2-4,13-15H2,1H3,(H,27,32,34)
• Chave InChI: InChIKey=RRAFWRVOUFGSEW-UHFFFAOYSA-N
• SMILES: COc1ccc(-n2nc(C(=O)NC=O)c3c2C(=O)N(c2ccc(N4CCCCC4=O)cc2)CC3)cc1