Gabexate Mesylate

CAS: 56974-61-9

Ref. TR-G122800

Informação sobre produto

• Nome: Gabexate Mesylate
• Sinónimos: ethyl 4-(6-carbamimidamidohexanoyloxy)benzoate;methanesulfonic acid, 39492-01-8, 4-[[6-[(Aminoiminomethyl)Amino]-1-Oxohexyl]Oxyl]Benzoic Acid Ethyl Ester Mesylate Salt, Arodate, Arodate (TN), Benzoic acid, 4-((6-((aminoiminomethyl)amino)-1-oxohexyl)oxy)-, ethyl ester, monomethanesulfonate, Benzoic acid, 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-, ethyl ester, methanesulfonate (1:1), Ethyl p-(6-guanidinohexanoxyloxy)benzoate methanesulfonate, Ethyl p-(6-guanidinohexanoyloxy) benzoate methanesulfonate, Ethyl p-hydroxybenzoate 6-guanidinohexanoate, FOY, Foy 007, Foy-S 983, Gabexate mesilate, Gabexate mesilate (JP14), Gabexate monomethanesulfonate, Gabexato [INN-Spanish], Gabexato mesilato [Spanish], Gabexatum [INN-Latin], Megacart, Megacert, Mesyl gabexate, Methanesulfonate, Reminaron, [N-[5-(4-ethoxycarbonylphenoxy)carbonylpentyl]carbamimidoyl]azanium, p-Hydroxybenzoic acid ethyl ester 6-guanidinohexanoate mesilate

Descrição

Applications Gabexate Mesylate is a serine protease inhibitor. Gabexate Mesylate inhibits trypsin, plasmin, plasma kallikrein and thrombin. Gabexate Mesylate inhibits lipopolysaccharide-induced tumor necrosis factor-α (TNF-α) production through nuclear factor-κB and activator protein-1 activation. Neuroresearch & Neuroprotective Product.
References Yuksel, M. et al.: J. Pharmacol. Exp. Therap., 305, 298 (2003); Tamura, Y. et al.: Biochim. Biophys. Acta, 484, 417 (1977); Ohno, H. et al.: Thromb. Res., 24, 445 (1981);

• Marca: TRC

Propriedades químicas

• Peso molecular: 417.48
• Fórmula: C₁₆H₂₃N₃O₄·CH₄O₃S
• Cor/forma: Neat
• InChI: InChI=1S/C16H23N3O4.CH4O3S/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18;1-5(2,3)4/h7-10H,2-6,11H2,1H3,(H4,17,18,19);1H3,(H,2,3,4)
• Chave InChI: InChIKey=DNTNDFLIKUKKOC-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1ccc(OC(=O)CCCCCNC(=N)N)cc1.CS(=O)(=O)O