Goserelin Acetate

CAS: 145781-92-6

Ref. TR-G767500

Informação sobre produto

• Nome: Goserelin Acetate
• Sinónimos: 1-9-Luteinizing hormone-releasing factor (swine), 6-[O-(1,1-dimethylethyl)-D-serine]-, 2-(aminocarbonyl)hydrazide, acetate (salt) (9CI), Luteinizing hormone-releasing factor (pig), 6-[O-(1,1-dimethylethyl)-D-serine]-10-deglycinamide-, 2-(aminocarbonyl)hydrazide, acetate (salt), Fertilan, Pyr-His-Trp-Ser-Tyr-D-Ser(Tbu)-Leu-Arg-Pro-Azagly-Nh2, [(T-Bu)Dser6, (Aza)Gly10]-Lh-Rh, [(T-Bu)Dser6, (Aza)Gly10]-Luteinizing Hormone-Releasing Hormone, Glp-His-Trp-Ser-Tyr-D-Ser(Tbu)-Leu-Arg-Pro-Aza-Gly-Nh2, (D-Ser(Tbu)6,Azagly10)-Lhrh, (D-Ser(tBu)6,Azagly10)-LHRH acetate salt, Goserelin HCl, Goserelin Hcl[Pyr-His-Trp-Ser-Tyr-D-Ser(T-Bu)-Leu-Arg-Pro-Azagly-Nh2], 5-oxoprolylhistidyl-N-[18,18-diamino-7-(tert-butoxymethyl)-13-({2-[(2-carbamoylhydrazinyl)carbonyl]pyrrolidin-1-yl}carbonyl)-4-(4-hydroxybenzyl)-1-(hydroxymethyl)-10-(2-methylpropyl)-2,5,8,11-tetraoxo-3,6,9,12,17-pentaazaoctadec-17-en-1-yl]tryptophanamide acetate (1:1), (2S)-N-[(2S,5S,8S,11S,14R,17S,20S)-25-amino-14-(tert-butoxymethyl)-20-({(2S)-2-[(2-carbamoylhydrazinyl)carbonyl]pyrrolidin-1-yl}carbonyl)-11-(4-hydroxybenzyl)-8-(hydroxymethyl)-1-(1H-imidazol-4-yl)-25-imino-5-(1H-indol-3-ylmethyl)-17-(2-methylpropyl)-3,6,9,12,15,18-hexaoxo-4,7,10,13,16,19,24-heptaazapentacosan-2-yl]-5-oxopyrrolidine-2-carboxamide acetate (1:1) (non-preferred name)

Descrição

Stability Hygroscopic
Applications Synthetic peptide agonist analog of LH-RH. Antineoplastic (hormonal).
References Clayton, R.N., et al.: Clin. Endocrinol., 22, 453 (1985), Gerris, J., et al.: Horm. Res., 45, 279 (1996),

• Marca: TRC

Propriedades químicas

• Peso molecular: 1329.46
• Fórmula: C₅₉H₈₄N₁₈O₁₄·C₂H₄O₂
• Cor/forma: Neat
• InChI: InChI=1S/C59H84N18O14.C2H4O2/c1-31(2)22-40(49(82)68-39(12-8-20-64-57(60)61)56(89)77-21-9-13-46(77)55(88)75-76-58(62)90)69-54(87)45(29-91-59(3,4)5)74-50(83)41(23-32-14-16-35(79)17-15-32)70-53(86)44(28-78)73-51(84)42(24-33-26-65-37-11-7-6-10-36(33)37)71-52(85)43(25-34-27-63-30-66-34)72-48(81)38-18-19-47(80)67-38, 1-2(3)4/h6-7,10-11,14-17,26-27,30-31,38-46,65,78-79H,8-9,12-13,18-25,28-29H2,1-5H3,(H,63,66)(H,67,80)(H,68,82)(H,69,87)(H,70,86)(H,71,85)(H,72,81)(H,73,84)(H,74,83)(H,75,88)(H4,60,61,64)(H3,62,76,90), /m0./s1, 1H3,(H,3,4)/t38-,39-,40-,41-,42-,43-,44-,45+,46-
• Chave InChI: InChIKey=IKDXDQDKCZPQSZ-JHYYTBFNSA-N
• SMILES: CC(=O)O.CC(C)C[C@H](NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)NNC(N)=O