N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-L-proline

CAS: 565453-40-9

Ref. TR-H296965

Informação sobre produto

• Nome: N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-L-proline
• Sinónimos: (2S)-1-[2-[(3-Hydroxyadamantan-1-yl)amino]acetyl]pyrrolidine-2-carboxylic Acid
• Marca: TRC

Descrição

Applications N-(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)glycyl-L-proline, is a metabolite of Vildagliptin (V305000), a class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase.
References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),

Propriedades químicas

• Peso molecular: 322.399
• Fórmula: C₁₇H₂₆N₂O₄
• Cor/forma: Neat
• InChI: InChI=1S/C17H26N2O4/c20-14(19-3-1-2-13(19)15(21)22)9-18-16-5-11-4-12(6-16)8-17(23,7-11)10-16/h11-13,18,23H,1-10H2,(H,21,22)/t11?,12?,13-,16?,17?/m0/s1
• Chave InChI: InChIKey=KWZNLUFQUDQQJU-FBXIQOIYSA-N
• SMILES: O=C(O)[C@@H]1CCCN1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2