Hydrocortisone 21-Valerate

CAS: 6678-00-8

Ref. TR-H714735

Informação sobre produto

• Nome: Hydrocortisone 21-Valerate
• Sinónimos: Cortisol 21-Valerate, 2-((8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl Pentanoate, (11Beta)-11,17-Dihydroxy-3,20-Dioxopregn-4-En-21-Yl Pentanoate, (11β)-11,17-Dihydroxy-21-[(1-oxopentyl)oxy]pregn-4-ene-3,20-dione, 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 21-valerate, Cortisol, 21-valerate, Hydrocortisone 21-valerate, Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-[(1-oxopentyl)oxy]-, (11β)-

Descrição

Applications Hydrocortisone 21-Valerate is a derivative of Hydrocortisone (H714615) a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
References O'Neill, R. et al.: J. Pharm. Pharmacol., 32, (1980); Vigore, L., et al.: Cancer Ther., 6, 699 (2008), Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009), Lemos, D., et al.: J. Endocrinol., 201, 275 (2009), Chen, S., et al.: Am. J. Physiol., 296 (2009),

• Marca: TRC

Propriedades químicas

• Peso molecular: 446.58
• Fórmula: C₂₆H₃₈O₆
• Cor/forma: Neat
• InChI: InChI=1S/C26H38O6/c1-4-5-6-22(30)32-15-21(29)26(31)12-10-19-18-8-7-16-13-17(27)9-11-24(16,2)23(18)20(28)14-25(19,26)3/h13,18-20,23,28,31H,4-12,14-15H2,1-3H3/t18-,19-,20-,23+,24-,25-,26-/m0/s1
• Chave InChI: InChIKey=XHDMDWMKAYYIRK-FZNHGJLXSA-N
• SMILES: CCCCC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C