p-Hydroxycocaine Hydrochloride

CAS: 197771-77-0

Ref. TR-H825445

Informação sobre produto

• Nome: p-Hydroxycocaine Hydrochloride
• Sinónimos: (1R,2R,3S,5S)-3-[(4-Hydroxybenzoyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester Hydrochloride, [1R-(exo,exo)]-3-[(4-Hydroxybenzoyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester Hydrochloride, 4'-Hydroxybenzoylecgonine Methyl Ester Hydrochloride, 4'-Hydroxycocaine Hydrochloride
• CAS: 197771-77-0

Descrição

Applications: p-Hydroxycocaine is a metabolite of Cocaine (HCl: C633500), a vasoconstrictive agent that is highly addictive and has high potential for abuse. The mechanism by which Cocaine induces dependence is unknown, but it is hypothesized that it works by blocking the dopamine transporter, increasing the amount of free dopamine in the brain.
References Carrera, M., et al.: Nature, 378, 727 (1995); Moore, T., et al.: Am. J. Obst. Gyne., 155, 883 (1986); Volkow, N., et al.: Nature, 386, 827 (1997)

• Marca: TRC

Propriedades químicas

• Peso molecular: 355.81
• Fórmula: C₁₇H₂₁NO₅•HCl
• Cor/forma: Neat
• InChI: InChI=1S/C17H21NO5.ClH/c1-18-11-5-8-13(18)15(17(21)22-2)14(9-11)23-16(20)10-3-6-12(19)7-4-10;/h3-4,6-7,11,13-15,19H,5,8-9H2,1-2H3;1H/t11-,13+,14-,15+;/m0./s1
• Chave InChI: InChIKey=AOSQZYJCIGWNGT-HLYGUNNVSA-N
• SMILES: COC(=O)[C@H]1[C@@H](OC(=O)c2ccc(O)cc2)C[C@@H]2CC[C@H]1N2C.Cl