di(2-Hydroxy Atorvastatin-d5) Calcium Salt

CAS: 265989-47-7

Ref. TR-H828932

Informação sobre produto

• Nome: di(2-Hydroxy Atorvastatin-d5) Calcium Salt
• Sinónimos: (ßR,dR)-2-(4-Fluorophenyl)-ß,d-dihydroxy-4-[[(2-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-phenyl-d5-1H-pyrrole-1-heptanoic Acid Calcium Salt (2:1)

Descrição

Applications di(2-Hydroxy Atorvastatin-d5) Calcium Salt is the labeled analogue of di(2-Hydroxy Atorvastatin) Calcium Salt (H828930), a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)

• Marca: TRC

Propriedades químicas

• Peso molecular: 1197.42
• Fórmula: C₆₆H₅₈D₁₀CaF₂N₄O₁₂
• Cor/forma: Neat
• SMILES: [2H]c1c([2H])c([2H])c(-c2c(C(=O)Nc3ccccc3O)c(C(C)C)n(CC[C@@H](O)C[C@@H](O)CC(=O)[O-])c2-c2ccc(F)cc2)c([2H])c1[2H].[Ca+2]