[S-(R*,S*)]-5-[1-Hydroxy-2-[(1-methyl-3-phenylpropyl)(phenylmethyl)amino]ethyl]-2-(phenylmethoxy)benzamide

CAS: 81580-37-2

Ref. TR-H945935

Informação sobre produto

• Nome: [S-(R*,S*)]-5-[1-Hydroxy-2-[(1-methyl-3-phenylpropyl)(phenylmethyl)amino]ethyl]-2-(phenylmethoxy)benzamide
• Sinónimos: 5-[(1S)-2-[benzyl-[(2R)-4-phenylbutan-2-yl]amino]-1-hydroxyethyl]-2-phenylmethoxybenzamide
• Marca: TRC

Descrição

Applications [S-(R*,S*)]-5-[1-Hydroxy-2-[(1-methyl-3-phenylpropyl)(phenylmethyl)amino]ethyl]-2-(phenylmethoxy)benzamide is an intermediate of (R,R)-Labetalol (L096500), a specific competitive antagonist at both α-and β-adrenergic receptor sites. (R,R)-Labetalol is used as an antihypertensive.
References Clifton, J. E., et al.: J. Med. Chem., 25, 670 (1982); Gold, E. H., et al.: J. Med. Chem., 25, 1363 (1982);

Propriedades químicas

• Peso molecular: 508.65
• Fórmula: C₃₃H₃₆N₂O₃
• Cor/forma: Neat
• InChI: InChI=1S/C33H36N2O3/c1-25(17-18-26-11-5-2-6-12-26)35(22-27-13-7-3-8-14-27)23-31(36)29-19-20-32(30(21-29)33(34)37)38-24-28-15-9-4-10-16-28/h2-16,19-21,25,31,36H,17-18,22-24H2,1H3,(H2,34,37)/t25-,31-/m1/s1
• Chave InChI: InChIKey=YJGVNAHSTICYPZ-OOWIMERYSA-N
• SMILES: C[C@H](CCc1ccccc1)N(Cc1ccccc1)C[C@@H](O)c1ccc(OCc2ccccc2)c(C(N)=O)c1