N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine

CAS: 808118-40-3

Ref. TR-H948180

Informação sobre produto

• Nome: N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine
• Sinónimos: Glycine, N-[(4-hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]-, (4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycine, ASP 1517, FG 4592, Roxadustat, [[(4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]amino]acetic acid
• Marca: TRC

Descrição

Applications N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine is a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor used to increase white blood cell levels in blood and hematopoietic progenitor cells in bone marrow.

Propriedades químicas

• Peso molecular: 352.34
• Fórmula: C₁₉H₁₆N₂O₅
• Cor/forma: Neat
• InChI: InChI=1S/C19H16N2O5/c1-11-15-9-13(26-12-5-3-2-4-6-12)7-8-14(15)18(24)17(21-11)19(25)20-10-16(22)23/h2-9,24H,10H2,1H3,(H,20,25)(H,22,23)
• Chave InChI: InChIKey=YOZBGTLTNGAVFU-UHFFFAOYSA-N
• SMILES: Cc1nc(C(=O)NCC(=O)O)c(O)c2ccc(Oc3ccccc3)cc12