1’-Hydroxy Midazolam

CAS: 59468-90-5

Ref. TR-H948420

Informação sobre produto

• Nome: 1’-Hydroxy Midazolam
• Sinónimos: 8-Chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-1-methanol, 1-Hydroxymidazolam, 1'-Hydroxymidazolam, Ro 21-6347, a-Hydroxymidazolam, alpha-Hydroxymidazolam, 4H-Imidazo(1,5-a)(1,4)benzodiazepine-1-methanol, 8-chloro-6-(2-fluorophenyl)-, 8-Chloro-6-(2-fluorophenyl)-4H-imidazo(1,5-a)(1,4)benzodiazepine-1-methanol, α-Hydroxymidazolam
• CAS: 59468-90-5

Descrição

Applications A metabolite of Midazolam (M343000(P)), which is an anesthetic; anticonvulsant; sedative; hypnotic. Midazolam is also a positive allosteric modulator of the GABAA receptor.
References Dundee, J., et al.: Drugs, 28, 519 (1984), Galetin, A., et al.: Drug Metab. Dispos., 30, 1512 (2002), Uchaipichat, V., et al.: Drug Metab. Dispos., 34, 449 (2006), Lewis, B., et al.: Biochem. Pharmacol., 73, 1463 (2007), Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)

• Marca: TRC

Propriedades químicas

• Peso molecular: 341.77
• Fórmula: C₁₈H₁₃ClFN₃O
• Cor/forma: Off-White
• InChI: InChI=1S/C18H13ClFN3O/c19-11-5-6-16-14(7-11)18(13-3-1-2-4-15(13)20)22-9-12-8-21-17(10-24)23(12)16/h1-8,24H,9-10H2
• Chave InChI: InChIKey=QHSMEGADRFZVNE-UHFFFAOYSA-N
• SMILES: OCc1ncc2n1-c1ccc(Cl)cc1C(c1ccccc1F)=NC2