1’-Hydroxy Midazolam-d5

CAS: 1276651-09-2

Ref. TR-H948423

Informação sobre produto

• Nome: 1’-Hydroxy Midazolam-d5
• Sinónimos: [8-Chloro-3,4,4-trideuterio-6-(2-fluorophenyl)imidazo[1,5-a][1,4]benzodiazepin-1-yl]-dideuteriomethanol, 8-Chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-1-(methanol-1,1-d2)-3,4,4-d3, 1-Hydroxymidazolam-d5, 1'-Hydroxymidazolam-1',1',3,4,4-d5, a-Hydroxymidazolam-d5, alpha-Hydroxymidazolam-d5, a-Hydroxymidazolam-a,a,3,4,4-D5

Descrição

Applications A labelled metabolite of Midazolam (M343000(P)), which is an anesthetic; anticonvulsant; sedative; hypnotic. Positive allosteric modulator of the GABAA receptor. Neuroprotective & Neuroresearch products.
References Dundee, J., et al.: Drugs, 28, 519 (1984), Galetin, A., et al.: Drug Metab. Dispos., 30, 1512(2002), Uchaipichat, V., et al.: Drug Metab. Dispos., 34, 449(2006), Lewis, B., et al.: Biochem. Pharmacol., 73, 1463(2007), Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)

• Marca: TRC

Propriedades químicas

• Peso molecular: 346.80
• Fórmula: C₁₈H₅H₈ClFN₃O
• Cor/forma: White To Off-White
• InChI: InChI=1S/C18H13ClFN3O/c19-11-5-6-16-14(7-11)18(13-3-1-2-4-15(13)20)22-9-12-8-21-17(10-24)23(12)16/h1-8,24H,9-10H2/i8D,9D2,10D2
• Chave InChI: InChIKey=QHSMEGADRFZVNE-UQJCUSATSA-N
• SMILES: [2H]c1nc(C([2H])([2H])O)n2c1C([2H])([2H])N=C(c1ccccc1F)c1cc(Cl)ccc1-2