1'-Hydroxy Midazolam-β-D-glucuronide

CAS: 81256-81-7

Ref. TR-H948430

Informação sobre produto

• Nome: 1'-Hydroxy Midazolam-β-D-glucuronide
• Sinónimos: β-D-Glucopyranosiduronic acid, [8-chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepin-1-yl]methyl, 4H-Imidazo[1,5-a][1,4]benzodiazepine, β-D-glucopyranosiduronic acid deriv., [8-Chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepin-1-yl]methyl β-D-glucopyranosiduronic acid, 1'-Hydroxymidazolam-β-D-glucuronide, α-Hydroxymidazolam-β-D-glucuronide
• Marca: TRC
• Descrição: Applications The major metabolite of Midazolam (M343000(P)). Midazolam is an anesthetic; anticonvulsant; sedative; hypnotic. It is a positive allosteric modulator of the GABAA receptor.References Dundee, J. W., et al.: Drugs, 28, 519 (1984), Lahat, E., et al.: Br. Med. J., 321, 83 (2000)

Propriedades químicas

• Peso molecular: 517.89
• Fórmula: C₂₄H₂₁ClFN₃O₇
• Cor/forma: White To Off-White
• InChI: InChI=1S/C24H21ClFN3O7/c25-11-5-6-16-14(7-11)18(13-3-1-2-4-15(13)26)28-9-12-8-27-17(29(12)16)10-35-24-21(32)19(30)20(31)22(36-24)23(33)34/h1-8,19-22,24,30-32H,9-10H2,(H,33,34)/t19-,20-,21+,22-,24+/m0/s1
• Chave InChI: InChIKey=ICIUMXQTLQXWGL-QMDPOKHVSA-N
• SMILES: O=C(O)[C@H]1O[C@@H](OCc2ncc3n2-c2ccc(Cl)cc2C(c2ccccc2F)=NC3)[C@H](O)[C@@H](O)[C@@H]1O